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Identification of Key Amino Acids Responsible for the Substantially Higher Affinities of Human Type 1 3-Hydroxysteroid Dehydrogenase/isomerase (3-HSD1) for Substrates, Coenzymes, and Inhibitors Relative to Human 3-HSD2

Segn Nrnberger y Mller la apariencia de la piel y de la PEFE es causada por herniaciones de la grasa, que protruyen desde la hipodermis a la parte inferior de una dermis donde la interfase dermo-hipodrmica se encuentra debilitada, lo que da como resultado la apariencia edematosa, fibrosa y nodular caracterstica 5

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