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[2] Mazdutides phase II trial in adults with obesity or excess weight showed approximately 10-14% weight loss at 4 mg and 6 mg doses over 32 to 48 weeks, with ongoing phase III trials investigating higher doses and effects on type 2 diabetes

Because even as branded drugs become more available and potentially cheaper, the same coverage restrictions, BMI cutoffs, and off-label barriers remain

Compounded topical treatments are tailored to improve delivery through the nail plate using ingredients such as terbinafine (fungicidal), ketoconazole (fungistatic), ibuprofen (anti-inflammatory), and DMSO (penetration enhancer)

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