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Epub 2010 Oct 13
In male Wistar rats experiencing transient ischemic stroke, UA suppresses the upregulation of cerebrocortical Vegfa expression in the acute phase of stroke and reduces the MMP-9/TIMP-1 ratio in the brain cortex, indicating that UA treatment may aid in the downregulation of the VEGF-A/MMP-9 pathway to improve BBB integrity [54]
28,48,49 Chondrocyte cell density starts to rise in the nucleus pulposus as cells start to migrate from the cartilaginous endplates and inner annulus fibrosis
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