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Beyond serving as structural components through the lipid bilayer, lipids participate in diverse cellular processes including the modulation of intracellular and intercellular signaling pathways, energy storage, and the synthesis and maintenance of myelin

Mice All experiments were approved by the animal ethics committee of Ghent University (EC2013-045, EC2014-065, EC2016-023, EC2017-055, EC2017-097, EC2017-098, EC2017-099, EC2019-013, EC2019-078, EC2020-082, EC2020-106), Antwerp University (2019-19), or by ethic committees and local authorities in Dresden (TVA 07/2021 Landesdirektion Sachsen) and conducted according to institutional, national and European animal regulations

For patients with T2DM who fail to achieve the glycemic target with adequate treatment with OHAs, proceed to insulin injection therapy

Arterioscler., Thromb., Vasc