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Stress Hormones Stress hormones play a significant role in weight loss

A study published in the New England Journal of Medicine showed a mean weight reduction of 24.2% at 48 weeks with the highest dose (12 mg), suggesting a potent step-change in efficacy

For a branded combination product generating $500 million annually, a 4.7-year device patent extension represents approximately $2.35 billion in revenue protected from generic competition, assuming full generic erosion would occur without the device patents