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Sesamin inhibits lipopolysaccharide-induced inflammation and extracellular matrix catabolism in rat intervertebral disc

FSP1 was suggested to be a type II NADH dehydrogenases (NDH-2) 36 that reduces quinone via shuttle reducing equivalents from NADH to flavin adenine dinucleotide (FAD) or flavin mononucleotide (FMN) through a ternary complex with both NAD(H) and quinone bound or a ping-pong mechanism, whereby the NAD+ has dissociated prior to quinone binding 37,38,39