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This finding is consistent with the broader observation that GHS-R1a receptors are expressed in multiple tissues beyond the pituitary, including kidney, heart, and immune cells, suggesting pleiotropic protective functions

Semaglutide weight reduction injections are available to adults with a BMI of 30 and higher and, in certain circumstances, a BMI of 27 and higher (in the event of weight-related health concerns)

Funding: The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: The article processing charge was covered by the University of Nebraska Medical Center

2024;385:e078242