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The co-culture of macrophages with ovarian cancer cells polarized macrophages toward the M2 phenotype, indicating that the tumor microenvironment favors the tumor-promoting M2 macrophages ( The polarization of TAMs is far more nuanced than previously thought, as various microenvironmental drivers shape their functional states

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The pancreatic tissue extracts for western blotting were prepared from four to six rats for each condition on experimental day P38