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[DOI] [PMC free article] [PubMed] [Google Scholar] 102.Elkins M, et al

Nausea appears to be common across all three medications

Mechanistically, the peptide has been studied as a pro-angiogenic agent that appears to work through the VEGFR2 receptor and the endothelial nitric-oxide synthase (eNOS)nitric-oxide pathway, and as a stimulator of fibroblast outgrowth and migration through the FAKpaxillin signaling pathway

Studies that include patients who are considered at-risk (i.e., diabetics, cardiac, elderly, etc.) and are currently taking GLP-1 RAs should also be performed as these patients may have compounding risk during the perioperative period which may make them more susceptible to complications related to GLP-1 use (Santos et al