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The American Diabetes Association upgraded GLP-1 agonists to preferred second-line agents for patients with cardiovascular comorbidities in its 2024 Standards of Care, elevating the drug class above sulfonylureas and DPP-4 inhibitors for many clinical scenarios

Smaller, low-fat meals throughout the day may reduce nighttime gastrointestinal symptoms

Wake and see natural light within 3045 minutes to anchor cortisol up, melatonin down, and set the clock that governs thyroid, insulin sensitivity, mood, and sleep

Fecal microbiota transplantation experiments suggest that transferring microbiota from treated animals to antibiotic-treated recipients can reproduce improvements in weight and insulin sensitivity, indicating microbial shifts may be functionally relevant rather than incidental