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For more on that side-effect experience, see why GLP-1 medications can make you tired

Risk of fracture with dipeptidyl peptidase-4 inhibitors, glucagon-like peptide-1 receptor agonists, or sodium-glucose cotransporter-2 inhibitors in patients with type 2 diabetes mellitus: A systematic review and network meta-analysis combining 177 randomized controlled trials with a median follow-up of 26 weeks

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When we consume food, this hormone is released by the intestines and helps to manage glucose levels via a few key mechanisms: Promoting Insulin Secretion When blood sugar rises after eating, GLP-1 stimulates the pancreas to release insulin, helping lower glucose levels