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Repeated exposure to stressors can overwhelm the protective mechanism of the pancreas and prompt the premature activation of digestive enzymes (e.g., trypsin), which in turn initiate the inflammatory cascade that promotes the auto-digestion of pancreatic tissue

Physiol Plant Pathol 27:311322 Dowdle J, Ishikawa T, Gatzek S, Rolinski S, Smirnoff N (2007) Two genes in Arabidopsis thaliana encoding GDP-L-galactose phosphorylase are required for ascorbate biosynthesis and seedling viability

The excessive use of vitamin D supplements without proper medical consultation can lead to vitamin D toxicity [156]

Reduced glutathione (GSH) is the only form that can actively neutralize free radicals and support detoxification