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146,147 Another critical limitation is the delay in predictive utility: the optimal scoring time point often occurs more than 48 h after symptom onset, at which time clinical signs of SAP are typically evident, potentially missing the window for effective early intervention

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However, in this case, the patients usually do not show symptoms of metabolic acidosis or hemolytic anemia, and antioxidant therapies are ineffective ( Table 2 Clinical features and laboratory data corresponding to patients diagnosed with GSSD in China