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The goal should be sustainable, steady progress under medical supervision

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Using the data, the researchers simulated seven clinical trials, testing what effect GLP-1s appeared to have on people with existing substance use disorders, as well as whether they appeared to prevent substance use disorders from developing

Several factors contribute directly to cognitive decline in people with CKD, including accumulation of uraemic toxins, microvascular damage, malnutrition, chronic inflammation and disruptions in key neuroprotective pathways, such as those involving Klotho and the glymphatic system