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In a study by Hostynek et al., three different layers of skin from human cadavers (isolated stratum corneum, isolated epidermis, and dermatomed skin) were employed to portray the penetration of GHKCu as a potential anti-inflammatory agent [69]

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CYP1A1 and CYP1B1 metabolize environmental polycyclic aromatic hydrocarbons (PAHs) and other xenobiotics alongside estrogens, generating reactive metabolites that GSTM1 and GSTT1 must also process