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Reported Adverse Effects From the limited human studies and anecdotal reports from users, the following side effects have been documented: Injection site pain and local reactions Joint pain or exacerbation of existing joint discomfort Anxiety and mood disturbances Palpitations and cardiovascular symptoms Insomnia or sleep disruption Nausea and gastrointestinal discomfort The frequency and severity of these effects remain unclear because no systematic adverse effect monitoring has been conducted across a large human population

In the Phase 2 trial, 72% of participants who had prediabetes at the start had normal glycated hemoglobin levels at 48 weeks, compared to just 22% on placebo

They are also the primary source of lycopene