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IP is generally believed to promote Ca release from intracellular stores, while DAG may recruit and activate protein kinase C (PKC)

However, a series of data points to an essential function of this vitamin on the SOD activity under oxidative stress

However, it is unclear if this abundance of thiomethyl derivates is related to a specific susceptibility of this individual to generate NAPQI metabolites, to the pregnancy itself (as sex steroids could be involved in the regulation of CYP2E1 ( 25 )) or to an accumulation of these metabolites in urine over time due to repeated intakes