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Furthermore, the functional relevance of endogenous neurogenesis is unclear due to the reduced survival of newborn cells in the striatum ( In addition to the striatum, several studies have found evidence that the cortex may also be capable of regeneration under certain conditions (Magavi et al., 2000), including after ischemia, albeit with a low number of newly formed neurons (Kornack and Rakic, 2001)

The HRH1 gene is located on chromosome 3p25 and is composed of 8 exons that generate four alternatively spliced mRNAs all of which encode the same 487 amino acid protein

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