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Bilirubin is a lipophilic molecule that accumulates in the cell, diffuses into the bloodstream, and then binds to circulating albumin to be transported to the liver

[4] The liver serves as the primary storage organ for B12 in cattle, accumulating the vitamin that is produced by bacteria in the rumen and then absorbed by the animal

Why Bioavailability Changes Everything If you decide to support your body with a supplement, the most important question is: "Does your body actually absorb this?" This is the concept of bioavailability, which refers to the proportion of a substance that enters the circulation when introduced into the body and is so able to have an active effect