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The Ozempic prescribing information lists three indications, all in type 2 diabetes: glycemic control, reduction of major adverse cardiovascular event risk in adults with established cardiovascular disease, and reduction of the risk of sustained eGFR decline, end-stage kidney disease and cardiovascular death in adults with chronic kidney disease

Each sample (8 l) was injected onto an Agilent Poroshell 120 EC-C18 (100 2.1 mm, 2.7 um) in a Shimadzu Nexera UHPLC system at a flowrate of 0.2 ml/min using a gradient elution created between buffer A (10 mM tributylamine aqueous solution adjusted pH to 4.95 with 15 mM acetic acid) and buffer B of methanol, from 10% to 40% (buffer B) in 30 min at room temperature

Infused with 50,000ppm of Glutathione (5%) and 950,000ppm of Collage

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