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However, two rare conditions may require more serious evaluation and treatment: Blepharospasm: 9 This condition affects about 20-50,000 Americans and can cause strong eyelid spasms that may keep the eye closed for hours at a time

It substantially narrowed the list of nominated ingredients, quickly reviewed each remaining substance and placed them into three categories

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Funding This research was supported by the Ratchadapisek Somphot Fund for Postdoctoral Fellowship, Chulalongkorn University (to G.K.) and Agricultural Research Development Agency, Thailand [Grant number CRP6405031890] (to S.S