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Based on these assessments, your doctor might adjust your treatment plan, recommend calcium and vitamin D supplementation at specific doses, prescribe bone-protective medications such as bisphosphonates if indicated, or refer you to an endocrinologist or osteoporosis specialist for complex cases, especially with fragility fractures, T-scores -2.5, or suspected secondary causes of bone loss

This original phase helps your body adjust to the medication

A simple blood test before starting semaglutide and periodic monitoring during treatment identifies who actually needs supplementation

It tends to show from around weeks 4 to 8, then builds over the following months as the dose increases