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Differentiating from Other Conditions Neurological signs and symptoms can be vitamin B12 deficiency associated or due to other causes such as: Pernicious anemia Syphilis Neurosyphilis Human immunodeficiency virus (HIV)-associated vacuolar myelopathy Toxic neuropathies Tropical myeloneuropathy Your healthcare provider can make a proper diagnosis based on your symptoms, medical history, physical exam, and laboratory test findings

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Although eye drops are widely used for the treatment of disorders affecting the anterior segment, there is yet to be successful clinical development of a topical eye drop that achieves therapeutically effective delivery to the retina

Although the field of cellular therapy has gained substantial clinical insights into optimizing CAR T cell therapy, the immunometabolic intricacies of CD19-CAR T cells in patients pre- and post-infusion have not been fully elucidated