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Although initial findings suggest that GLP-1Ra leads to a slight reduction in bone mineral density and promotes bone remodeling, favoring resorption similar to calorie restriction effects, further research is needed to explore the effects of GLP-1Ra on bone metabolism and fracture-related outcomes, as well as dual- and triple-receptor agonists of GLP-1, glucose-dependent insulinotropic polypeptide (GIP), and glucagon in PwO

Additionally, because of the sedentary lifestyle associated with OA, it increases cardiovascular mortality by more than 50%, necessitating its listing in 2018 as a severe disease by the Food and Drug Administration (FDA) 5

Stifles Inflammation: May target chronic inflammation to support joint health and reduce pain

If thyroid hormone levels are too loweither due to untreated hypothyroidism or suboptimal treatmentyour basal metabolic rate drops