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During I/R injury, the intestinal barrier becomes weakened, allowing microbial translocation, endotoxins, and inflammatory mediators such as cytokines to enter the bloodstream

culture wells coated with 5 g/mL) in the presence of Th1- or Th2-skewed conditions (Th1: addition of IL-12 [R&D System, 419-ML, 5 ng/mL], anti-IL-4 [R&D System, 404-ML-050/CF, 1 ng/mL] and IL-2 [R&D System, 402-ML-100/CF, 20 ng/mL]

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Mitochondrial Membrane Potential Regulates Nuclear Gene Expression in Macrophages Exposed to Prostaglandin E2