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Consistent topical use can produce meaningful improvements in surface texture and hydration, particularly when applied post-microneedling when the barrier has been temporarily disrupted
Therefore, there is the existence of a family of angiogenic peptides [71], and the removal of an angiogenic stimulus leads to the regression of neovascularization and tumor growth [72]
These peptides have not been proven safe or effective through the rigorous clinical trial process that FDA-approved drugs must pass
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