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When supplemented, GBB dramatically increases both plasma and urinary carnitine levels -- research shows it can boost carnitine excretion up to 40-fold compared to baseline

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Overall, these results indicate GLP-1RAs can influence a number of proteinopathies across disease models, although more understanding is required to determine when in the course of disease proteostasis can be modulated to bring about reduced neuronal loss and clinical benefit

doi: 10.1016/j.mayocp.2017.12.003 50 MagnussonIRothmanDLKatzLDShulmanRGShulmanGI