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Those with pre-existing conditions such as irritable bowel syndrome (IBS), functional dyspepsia, or gastritis may be more prone to experiencing stomach upset from supplements generally, including B12 preparations

For example, riboflavin contains a yellow-green pigment with fluorescent hues, says StatPearls

Both types of injections are generally administered intramuscularly and are often used in conjunction with other treatments or lifestyle changes to maximize their benefits

Acute symptoms such as fatigue may improve relatively quickly, whereas neurological symptoms like paraesthesia (pins and needles) or cognitive difficulties typically require longer treatment courses