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Eder 2015

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Flavonoids ameliorate ototoxic drug-induced hearing impairment by acting as ROS scavengers or inhibitors of JNK, MAPK, and other apoptotic signaling pathways, and by inhibiting aldose reductase activity, xanthine oxidase ( 3.1.1 Puerarin Puerarin, one of the major components of Pueraria lobata, has been reported to have a wide range of pharmacological activities, including anti-inflammatory, antioxidant and anti-apoptotic effects

doi: 10.1016/j.abb.2017.09.009 119