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2 This is explained in part by the fact that there is often a delay in diagnosis due to uncharacteristic morphologies

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47,239 Based on the recruited adapter proteins, TLR signaling pathways have been classified into two distinct categories: MyD88-dependent (in all TLRs except TLR3) and MyD88-independent (also known as the TIR domain-containing adapter-inducing interferon- (TRIF)-dependent pathway)