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Inactivated KCs maintain NF-B in the cytoplasm via the inhibitory KB protein (IKB), whereas in activated KCs, the inhibitory KB kinase (IKK) phosphorylates IKB, releasing NF-KB into the nucleus in response to various extracellular stimuli, such as LPS and complement C3/C5

Metallothioneine, die wichtigsten intrazellularen Kupferspeicherproteine, werden durch GHK-Cu ebenfalls hochreguliert, was einen zusaetzlichen Schutzmechanismus gegen Kupfer-induzierte Toxizitaet darstellt

5 The most common finding is hyperintensity on T2 weighted images involving the basal ganglia and substantia nigra

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