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GIP appears to amplify the metabolic benefits of glucagon activation in ways that neither receptor achieves alone

To compare the effects of paraxanthine against caffeine and the impact of age, young 8-week-old (YOUNG) and aged 16-month-old (OLD) rats were evenly divided into four groups ( n = 8 per group): (i) vehicle control (CON), (ii) low-dose paraxanthine (PXN LOW), (iii) high-dose paraxanthine (PXN HIGH), and (iv) high-dose caffeine (CAF HIGH)

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