MG is detoxified by the glyoxalase route by the sequential actions of GLYI and GLYII in a glutathione (GSH)-dependent manner, while GLYIII facilitates glutathione-independent detoxification under prolonged stress conditions
Back to Journals Journal of Inflammation Research Volume 14 IGF-1 Facilitates Cartilage Reconstruction by Regulating PI3K/AKT, MAPK, and NF-kB Signaling in Rabbit Osteoarthritis Authors Hossain MA , Adithan A, Alam MJ, Kopalli SR, Kim B, Kang CW, Hwang KC, Kim JH Received 20 April 2021 Accepted for publication 12 July 2021 Published 24 July 2021 Volume 2021:14 Pages 35553568 DOI Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Professor Ning Quan Mohammad Amjad Hossain, 1 Aravinthan Adithan, 1 Md Jahangir Alam, 1 Spandana Rajendra Kopalli, 2 Bumseok Kim, 1 Chang-Won Kang, 1 Ki-Chul Hwang, 3 Jong-Hoon Kim 1 1 College of Veterinary Medicine, Biosafety Research Institute, Chonbuk National University, Iksan-city, Jeollabuk-Do, Republic of Korea
Low-density lipoprotein (LDL) - a particle that carries cholesterol from the liver to all cells in the body Observational study - a human research study in which no experimental intervention or treatment is applied, and participants are simply observed over time Oxidative damage - damage caused by reactive oxygen species Placebo - a chemically inactive substance Randomized controlled trial - a human research study in which participants are assigned by chance alone to receive either an experimental agent (the treatment group) or a placebo (the control group) Reactive oxygen species (ROS) - highly unstable oxygen-containing compounds that react easily with nearby cellular structures, potentially causing damage Test tube - a research experiment performed in a test tube, culture dish, or other artificial environment outside of a living organism
Zhang JJ, Wu ZB, et al
