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The opioid receptor hypothesis A separate line of work proposed that DSIP possesses agonist activity at opiate receptors a hypothesis explicit in the title of the principal human withdrawal paper, which describes DSIP as a neuropeptide with potential agonistic activity on opiate receptors. [13] Supporting animal evidence came from Scherschlichts group, where DSIP at 25.5 mcg/kg IV attenuated naloxone-precipitated withdrawal jumping in morphine-dependent mice

The brain receives satiety signals from two completely independent pathways

Replicate analyses to determine repeatability resulted in intra- and inter-assay coefficients of variation of 410%, providing users with confidence in assay performance

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