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Alpha-melanocyte-stimulating hormone and related tripeptides: biochemistry, antiinflammatory and protective effects in vitro and in vivo, and future perspectives for the treatment of immune-mediated inflammatory diseases. Endocrine Reviews , 29(5), 581602

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Studies in adults indicate high relapse rates after withdrawal (25%88%), even in those with prolonged biochemical remission [145,146,147,148,149,150,151,152]