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Henry RR, Mudaliar SR, Howland WC 3rd, et al

Alzheimers disease (AD) is the most common neurodegenerative disorder characterized by cognitive impairment, and iron levels in the hippocampus, which are severely impaired in AD patients, are significantly elevated 59

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The second question relates to what was described as perceived excessive weight loss in the extension period of the SURMOUNT-1 study, where dose modifications of the blinded study drug were allowed to support patient management and retention during the additional two-year treatment phase