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Check with your doctor immediately if any of the following side effects occur: Some side effects may occur that usually do not need medical attention

Starting cagrilintide when already on retatrutide If you are already established on retatrutide at a stable dose (meaning you have been at your current retatrutide dose for at least four weeks without significant GI issues), you can introduce cagrilintide at its lowest starting dose of 0.25 mg weekly

The Phase 2 Numbers Amgen reported topline Phase 2 results in November 2025 and presented detailed data at the American Diabetes Association meeting in June 2025

Allergic Reactions : Although rare, some people may experience allergic reactions