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Merbach A

Multiple cytokines and inflammatory factors participate in keloid formation, such as transforming growth factor 1(TGF-1), vascular endothelial growth factor (VEGF), interleukin (IL)-1, IL-6, and IL-8, as well as increased matrix metalloproteinases (MMP S ), which may promote fibroblast proliferation and migration, the inflammatory response, and collagen production 2,3,4

Stretch the wrist extensors by gently bending your wrist downward with the elbow straight

An individual with a history of cardiovascular diseases, miscarriage or one who experiences fatigue, loss of appetite, low energy, anemia and has frequent mood swings and irritability may also have similar signs as for folate deficiency