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In the phase 2 diabetes trial, retatrutide reduced liver fat by up to 82% at the 12 mg dose, with over 80% of participants achieving normalization of liver fat content (Hartman et al., presented at EASL 2023)

Weston, a clear picture of progress is another strong motivator

Second, some associations, including the association with CAD, did not reach Bonferroni-corrected significance, so we cannot exclude the possibility of a chance finding