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Oxygen sensing, hypoxia-inducible factors, and disease pathophysiology

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(1974) Methylation of nucleic acids by 2,2-dichlorovinyl dimethyl phosphate (dichlorvos, DDVP)

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Metformin can activate the AMPK pathway, influencing the downstream AKT pathway to regulate subsequent molecules [18]

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This accumulation further drives microglial polarization toward the pro-inflammatory M1 phenotype

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