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developed vitamin C-lipid supramolecular nanoassemblies and demonstrated in DSS-induced colitis mice that this strategy significantly ameliorated disease severity, reduced inflammatory burden, and reshaped the gut microbial profile, thereby suggesting a potential role for vitamin-based interventions in modulating intestinal inflammation and microbiota homeostasis 206

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In this study, we induced senescence in A375 cells using doxorubicin and confirmed cellular senescence through senescence-associated beta-galactosidase (SA--gal) staining (Figure