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Data extraction and synthesis were conducted in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines to ensure methodological transparency and rigor

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(2) Based on the blood glucose results, the mice were subsequently re-randomized into a normal saline control group and a 2 g/kg Exendin-4 intervention group (n = 6)

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Primary effects: All effects of dual agonists plus increased energy expenditure through thermogenesis, enhanced fat oxidation and lipolysis, potential brown fat activation, direct hepatic effects reducing liver fat

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Thats a real and fairly consistent finding

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