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When she reiterated that he put in the work to lose 140 pounds naturally, he made it clear that he supports the use of weight loss injectables like Ozempic, but had his own reasons not to use them

The durability of the glucagon-mediated metabolic changes after drug washout is an open research question that Phase 3 extension studies are expected to address

Importantly, minimal regain occurred between plateau and study completion, suggesting sustained metabolic benefits

Pregnancy is listed as a situation where GLP-1 therapy is not recommended, with discontinuation timing to be discussed if conception is planned