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FIGURE 5 GSK3 negatively regulates CBS activity The transcription factor NF-E2-related factor 2 (Nrf2) encodes a protein which has a short half-time of only 30 min and which stability is controlled through the regulation of its turnover by the ubiquitin-proteasome system

The homogenate was centrifuged (4 C, 10 min, 13,200 g)

PEG increases the shelf-life of drug molecules and is used in the brain to target various drug molecules

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