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For example, nigral neurons are less abundant with the L-type Ca 2+ channels and are characterized by low oscillations of Ca 2+ , more expressed calcium-binding proteins calbindins, and therefore exhibit lower susceptibility to damage in PD (Khaliq and Bean 2010)

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Exendin-4 from Gila monster venom shares structural similarities with human GLP-1 but has a significantly longer duration of action due to resistance to DPP-4 enzyme breakdown

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