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In most cases this is a protective response
NEWS Correction 06 January 2026 Update 08 January 2026 2025 FDA approvals Access options Access Nature and 54 other Nature Portfolio journals Get Nature+, our best-value online-access subscription $32.99 / 30 days cancel any time Subscribe to this journal Receive 12 print issues and online access $259.00 per year only $21.58 per issue Rent or buy this article Prices vary by article type from$1.95 to$39.95 Prices may be subject to local taxes which are calculated during checkout Nature Reviews Drug Discovery 25 , 81-87 (2026) doi: Updates & Corrections Correction 06 January 2026 : The brand names of Nuvaxovid and Mnexspike have been corrected in Table 2
Nausea, changes in skin color, and hormonal effects are only part of the picture
In contrast, heat shock protein B1 (HSPB1) counteracts the increased expression of TFR1 and thus reduces the intracellular iron to inhibit ferroptosis [43]
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