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doi: 10.1093/ckj/sfac274

Two-thirds of patients stopped taking the drugs within a year of starting them, according to one recent analysis of insurance claims

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In the setting of TBI, the oxidative cascade overwhelms endogenous antioxidants (e.g., superoxide dismutase and catalase) and low-molecular antioxidants (e.g., glutathione and melatonin, tocopherol, and ascorbic acid), resulting in cell injury and death