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Pharmacologically, cysteine availability can be augmented by N-acetylcysteine (NAC), which is deacetylated intracellularly to supply cysteine for GSH synthesis 22

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Last Published 01.01.2026 Effective Date: 01.01.2026 This policy addresses the use of Luxturna (voretigene neparvovec-rzyl) for the treatment of inherited retinal dystrophies (IRD) caused by mutations in the retinal pigment epithelium-specific protein 65kDa (RPE65) gene