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160 MssnerR.HennebergA.SchmittA.SyagailoY.GrssleM.HennigT.et al (2001)

Most adverse effects can be minimized or avoided altogether with a well-planned protocol and proper support

Studies in fly models of PD treated with NAM, NAD + , or through PARP mutations demonstrated increased NAD + levels, which also rescued mitochondrial function 283,284,285