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To test this hypothesis, we evaluated sperm parameters, reproductive hormone levels (testosterone, FSH, and LH), testicular antioxidant markers (catalase, superoxide dismutase, glutathione S-transferase, and reduced glutathione), lipid peroxidation (TBARS), and performed histopathological examination of the testes

J Clin Tran Endo, 2024

Glucagon-like peptide-1/glucose-dependent insulinotropic polypeptide dual receptor agonist DACH5 is superior to exendin-4 in protecting neurons in the 6-hydroxydopamine rat Parkinson model

This suggests that although there is a reduction in lean mass with semaglutide treatment, there is an improvement in muscle function